The road was closed at Ohio 4 due to the crash.
When police arrived, they found that the driver and only occupant of one vehicle had died at the scene, the Middletown Division of Police said this morning.
The driver and only occupant of the second vehicle suffered a “potentially serious injury” and was taken by the Middletown Division of Fire to Atrium Medical Center for treatment, according to police.
The Middletown Traffic Unit and Butler County Sheriff’s Office Severe Accident Reconstruction Team was called out and responded to the scene, police said.
The crash remains under investigation.
Anyone with information regarding the crash is asked to call Middletown police at 513-425-7918 to speak with Sgt. Ryan Rogers or officer Scott Renner.


